Fans are hoping she could return to play the character Amy from the Chuck Lorre-created sitcom, which premiered in 2007 and ran for 12 seasons.
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Mayim Bialik would be 'very flattered' to appear in 'The Big Bang Theory' spin-off

Although "The Big Bang Theory" has ended, she recently reconnected with her former co-star Melissa Rauch on her NBC show "Night Court." While promoting the show, she said Us Weekly that she has not been contacted about appearing on the show, but would like to return.
"I have not been contacted," she confirmed. "I saw what was announced and I think that's where a lot of people know about it (now) — I'm one of them."
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Mayim Bialik likes to be known for her role as Amy

“These characters were so iconic and so meaningful to people. (Creators) Chuck (Lorre) and Bill (Prady) have really created a world of characters that people want to know about and follow,” she continued. "So I'm very flattered and would be very flattered to be contacted."
She went on to say, “I love being known as that character and I love what that means to people. So it would be a thrill for me to be a part of that in any way.”
“It was a really, really fun experience to be a part of (during my guest appearance with Jim Parsons) on Young Sheldon,” she added. "I also get to interact with (creators) Steven (Molaro) and Steve (Holland) and a lot of our writers and producers, so it's a whole world that I still feel very connected to."
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Mayim Bialik talks to Melissa Rauch again
On Tuesday, Jan. 14, the “Blossom” child star played an “exaggerated version” of herself when she appeared in Rauch's comedy “Night Court.”
“I left the creative (details) up to Melissa when she asked me if I would be interested in coming. I literally told her, 'Whatever you want, I'll be happy to do it.' It's just out of a sense of camaraderie and support for her and our friendship," Bialik told the publication.
“I'm also really proud of everything she's created. I was just happy to cheer – and I'm also a fan of Night Court,” she continued. "When I was little, I wasn't allowed to watch him because he was naughty and had a bit of a sharp tongue."
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Mayim Bialik reveals the challenges of playing herself
“Melissa asked how I felt about this idea of playing a twisted version of myself. I said I'll be as silly as you want and as crazy as you want. Melissa also drew on our real-life story where she was a fan of Blossom, and when we started working together on The Big Bang Theory, she discovered that,” Bialik explained. “I loved the idea of playing with this and art imitating life.”
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“The advantage is that there's a certain amount of ease that comes with playing alone. You don't create a character. I know the background because it's mine,” she continued. “But as far as cons go, it's tough — especially if you're playing an exaggerated version. The producers have to ask themselves, 'Oh, is she afraid people will think she's really like that?' Or like, 'What's that exaggerated version going to be?'”
"But I don't see it as a big obstacle," she added. "It's definitely a challenge to try to stretch beyond playing yourself, but also playing an exaggerated version of yourself."
'The Big Bang Theory' spawned two spin-off shows

During its original run from 2007 to 2019, the CBS comedy picked up 10 Emmy Awards and spawned two prequel series: “Young Sheldon” and “Georgie and Mandy's First Marriage.”
Warner Bros. The network is currently working on a spin-off series that would star Brian Posehn, Lauren Lapkus and Kevin Sussman, who would reprise their roles from the original series.
If the series gets picked up, it will air on Max.
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