Demi Moore won her first Golden Globe at the 82nd Golden Globe Awards in Los Angeles on Sunday.

The 62-year-old actress won best actress in a motion picture — musical or comedy for her role in "Substance."

The Golden Globe is the first major acting award won by Demi Moore.

Demi Moore won her first major acting award at the 82nd Golden Globe Awards on January 5

Moore won for her role as Elisabeth Sparkle in the horror/sci-fi film "The Substance." In the film, Moore plays a famous and aging aerobics instructor who is fired because of her age.

In the film, a desperate Sparkle takes a cell-replicating substance that temporarily creates a younger, better clone who tries to take over her life (played by Margaret Qualley).

The "GI Jane" actress was humbled during her acceptance speech and said she was "in shock" CBS.

“Oh, wow! I really didn't expect it,” Moore said of her historic victory. “I'm in shock right now. I've been doing this for a long time – over 45 years, and this is the first time I've won anything as an actor. And I'm so humbled and grateful."

Moore added that thirty years ago, a producer told her that she was just a "popcorn" actress, and even though she could be successful in the industry and make a lot of money, she would never be recognized.

"I accepted it and believed it," Moore said. "It ate away at me over time to the point where a few years ago I thought maybe this is it, maybe I'm complete, maybe I've done what I'm supposed to do, and I was kind of at a low point. This magical, brave, brave, a finished, completely insane script came across my desk called 'Substance'."

Entertainment Tonight caught up with the actress after her win, and she said her acceptance speech came from the heart.

"I was in such shock, I must say," she said. "I didn't expect all that. I think it just poured out."

The star of "A few good people" was shown a video of her three daughters with her ex-husband Bruce Willis - Scout, Tallulah and Rumer - react excitedly to her Golden Globe win.

“Oh my god! They're a loud audience," she exclaimed. "The reality is, as I realized, there were so many people I didn't get a chance to thank. And the truth is that everything I do is for them. It's for my daughters, for my daughter's daughter. And I hope the same way that translates to all women. I am so grateful that I can be a part of paving a new path, a new way for women to be seen, the things we can do. And I'm not the answer, but I'm becoming a small piece."

Moore began her career in entertainment on the ABC soap "General Hospital" when she was just 19 years old.

The young actress soon landed a role in "Blame it on Rio" before moving on to lead roles in hits such as "No Small Affair" and "St. Elmo's Fire." In 1990, Moore starred in the movie "Ghost" with Patrick Swayze and Whoopi Goldbergand soon became the highest paid actress in Hollywood.

She went on to star in several more films including "A Few Good Men," "Indecent Proposal" and "The Juror."

Moore currently stars in Paramount's "Landman" with Billy Bob Thornton.

According to The Hollywood Reportermost of Moore's scenes in "The Substance" feature the actress without dialogue.

"The script was such an interesting, unusual read, the way it explores the issue of aging," Moore said. "What caught me was the exploration of violence that we can have against ourselves, in the way that we can dissect and criticize. I've found, at least in my own experience in life, that it's really not what anyone else has done to me. The influence has always been on what I do to myself, internalized."

"So it was all kind of weird, intimate that we have with ourselves, where we're often naked, looking, dissecting, thinking," she continued. "It was a really interesting challenge to create a full life for her because I didn't have anyone to feed off of. It was also very technical."